Why is it important?

Economic and decision models are essential tools, providing quantitative assessments of the value of a given intervention. They are used to support the preparation of dossiers for HTA agencies’ and payers’ appraisals as well as for making an informed strategic decision. These models are generally used for cost-effectiveness and budget impact analyses as well as to determine the patient population that can benefit the most from treatment or designing an optimal vaccination campaign, among other strategic decisions.

What we do at Creativ-Ceutical

At Creativ-Ceutical, we develop many types of models, such as decision trees, Markov models, discrete event simulations, and dynamic transmission models. Creativ-Ceutical has established several internal tools and procedures that guarantee adherence to the best practices, as well as ensure the quality control of each model. We make flexible models with user-friendly interfaces to facilitate their use and for further potential adaptations.

Our track record

With health economic modeling as one of the core areas of expertise in Creativ-Ceutical, we develop over 20 economic models every year. Our experience in working with different pathologies and therapeutic areas allows us to design models which adequately capture the entire benefits of a particular health technology. This strategic know-how is combined with the strong technical and statistical skills of our highly qualified developers and analysts.

Geographical coverage of our modeling expertise

Models developed by Creativ-Ceutical have been used in successful HTA submissions, such as submissions to the NICE (UK), SMC (Scotland), and HAS (France), TLV (Sweden), etc. For our clients in the USA, we have developed models used for AMCP dossiers as well as for the submissions to the ACIP (Advisory Committee on Immunization Practices). Creativ-Ceutical has also developed models tailored to Asia Pacific and Latin American submissions.


Extension of the existing models (inclusion of new comparators, treatment pathways)


Model conceptualization and development


Global management, support, and supervision of concurrent local adaptations


Local adaptation of existing models


Update of existing models with the most recent input data


Critical appraisal of existing health-economic models