Schizophrenia is a psychiatric illness that associates thought process disintegration and poor emotional responsiveness. The S-QoL is a self-administered questionnaire that assesses quality of life (QoL) among people with schizophrenia. The scale is a 41-item questionnaire with eight subscales (psychological well-being, self-esteem, family relationships, relationship with friends, resilience, physical well-being, autonomy and sentimental life). The objective of this study was to validate the Russian version of S-QoL.