Benzodiazepine discontinuation with prolonged-release melatonin: hints from a German longitudinal prescription database

Benzodiazepine discontinuation with prolonged-release melatonin: hints from a German longitudinal prescription database

2012 Expert. Opin. Pharmacother

Kunz, D. | Bineau, S. | Maman, K. | Milea, D. | Toumi, M. | Volume: 13, Issue: 1, Pages: 9-16, Aged, Benzodiazepines, Delayed-Action Preparations, drug therapy, Europe, Female, Germany, Humans, Hypnotics and Sedatives, Male, Melatonin, methods, Middle Aged, Research Design, Retrospective Studies, Sleep Initiation and Maintenance Disorders, therapeutic use, database analysis,

OBJECTIVE: Prolonged-release (PR) melatonin is approved in Europe for the treatment of insomnia in patients aged 55 years and above. The objective of the study was to describe its prescription patterns and its impact on hypnotics use in routine clinical practice. RESEARCH DESIGN AND METHODS: This is a retrospective study analyzing PR melatonin prescription data from a German longitudinal database (IMS((R)) Disease Analyzer). All patients initiating PR melatonin over the 10 months after approval (April 2

https://www.doi.org/10.1517/14656566.2012.638284